MadSci Network: Biochemistry |
Hi Evan pH levels in biological systems is very important, as you might have discussed in your chemistry class. To keep our blood at about pH 7.4 our body uses three different types of buffers. pH is controlled by the concentration of hydrogen atoms - H+ - in a solution. Buffers work to lower pH (make your blood more acidic if the level is above 7.4) by releasing hydrogen atoms into your blood. The reverse happens if your blood is too acidic; hydrogen atoms are taken up by the buffers, decreasing the H+ concentration and increasing pH. There are three classes of blood buffers. The first two you already know about. These are phosphate buffers which change between [H2PO4](-1) and [HPO4](-2). While used in the blood buffer system, phosphate buffers are very important in the urinary buffer system. The 2nd type are the bicarbonate buffers. These change between [HCO3](-1) and [H2CO3]. Now, to answer your question. The 3rd type of buffers are protein buffers. These are probably the most important out of the three types found in the blood system. They include proteins such as hemoglobin (the protein that carries oxygen through your blood). Buffer proteins contain basic and acidic groups that may either act as hydrogen ion acceptors or donors to help maintain blood pH. I hope that answers your question for you. ~Ashley Calder PS: I found most of this information by typing "blood buffers" into a search engine... this is the website I used: pH of the Blood: Acid-Base Balance PPS: The numbers in brackets after the bicarbonate/phosphate formulae are to indicate the overall charge of the whole molecule.
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