MadSci Network: Medicine |
Dear Mr. Wagoner, The egg is non-motile, as is the embryo. However, the fallopian tube is ciliated and pushes the cell along. The cilia activity seems to be under the positive influence of estradiol 17-beta, which drops for a few days during mid-cycle (ovulation time) and then increases again as the follicle reorganizes as a corpus luteum several days after ovulation. Thus the egg, or embryo if fertilization has taken place, hangs out in the fallopian tube for about 3 days (low estradiol) until the estradiol starts to increase and the cilia sweep it down to the uterus. Once in the uterus the embryo hangs out for about another 3 or 4 days until it hatches and can then implant into the endometrium. If it is an unfertilized egg, then it will be lost a week or so later in the menstrual flow when the endometrium is sloughed off. Dr. Swanson
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