MadSci Network: Genetics
Query:

Re: How are DNA, mRNA, and tRNA related? What are base pairs?

Date: Mon Feb 28 20:40:24 2000
Posted By: Joyce Siew, Undergraduate, Biology, National University of Singapore
Area of science: Genetics
ID: 951711925.Ge
Message:

Dear Gabe,



mRNA and tRNA are transcribed from one of the double helix DNA strands.
Their transcription are based on the complementary base pairings using 
Watson-Crick base pairings. That is, the trancription of any RNA from a 
DNA template must follows this rule:

a) A pairs with U
b) C pairs with G
c) T pairs with A

mRNA are tRNA are needed in protein synthesis. You can say that they are 
really 'made' (transcribed from DNA) and probably that's what your teacher 
meant by their relationship to DNA.

The base pairs that you refer to are the complementary base pairings due 
to hydrogen bonds formed between the purine and pyrimidine bases. Purine 
bases are Adenine and Guanine and pyrimidine bases are Cytosine, Uracil, 
and Thymine. There are 2 H-bonds formed bewteen A-U or A-T and 3 H-bonds 
bewteen C-G.

I hope this clear your doubt.

In my experience of studying genetics, you really should approach your 
teacher if you have any doubt. She is the best person to guide you. Good 
Luck!!

Reference:

1) Any genetics textbooks.



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