| MadSci Network: Neuroscience |
Dear Karen, I am not quite sure what exactly what events you are talking about. The question I really answered is this: "I have had some asthma attacks and feel a little different, sort of like a different person. Why is this?" First, I am to clear up a misconception. CPR does not restart the heart. CPR keeps blood circulating, mostly to the heart and brain and provides oxygen to the lungs so that the blood that is circulating contains oxygen. Drugs that are given during CPR, like adrenaline (epinephrine), atropine and lidocaine, help the heart beat stronger and help keep the heart beating in rhythm. Shock the heart (cardioversion) helps the heart become properly resyncrhonized (it does not really restart the heart either). During such severe events like a severe asthma attack or something requireing CPR, there are many drugs used (like epinephrine [andrenaline] and steriods); the body makes many different hormones, like epinephrine and streriod hormones, both from the adrenal glands. Not only can these drugs and hormones help the body recover, they can also have profound effects on the brain and personality, especially the steriod hormones. Personality changes are common side effects of steriod hormones. In addition, after a severe asthma attack, patients are often on steriod hormones for a while. I suspect this is what is causing you to feel as if you are a different person. Now to answer the first part of your question. After your brain is short of oxygen for a period (which probably is NOT happening during an asthma attack -- the hospitals monitor the oxygen levels in your blood pretty closely), brain damage can affect the personality. How much depends on which areas of the brain are damaged and how badly damaged they are. If the brain is indeed damaged by oxygen starvation, how the person's personality will change and for how long will depend on where the brain is damaged and the type and severity of damage. One of the things that we are supposed to do is provide references or web pages that provide further information. Unfortunately, I was unable to find good references for you. Thanks for your excellent question. Jeff Utz
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