MadSci Network: Development

Re: What happens if two sperms bind onto an ovum at exactly the same time?

Area: Development
Posted By: Brian Hyatt, Grad student Cell Biology and Neuroanatomy
Date: Fri Apr 18 10:53:56 1997
Area of science: Development
ID: 861106337.Dv
If more than one sperm fuses with an egg (referred to as polyspermy), 
extra mitotic spindles form which results in abnormal segregation of
chromosomes during cleavage, non-diploid cells are produced, and 
development quickly stops.  This illustrates why eggs have such 
effective blocks against fertilization by more than one sperm.
Information taken from "Molecular Biology of the Cell"
2nd edition, Bruce Alberts et al.

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