| MadSci Network: Molecular Biology |
Jumping genes are genetic elements which are called Transposons or Transposable element (sometimes they are also called Insertion Elements or Insertion Sequences). These terms all mean the same thing and refer to segments of DNA which can move from one location on a chromosome to another location, or to another chromosome. Where do they jump to? That really depends upon the element itself and whether it has any specificity for a target sequence. These elements use proteins to make a cut in the DNA into which they can insert or replicate themselves. Sometimes this cut is random and can occur almost anywhere, other proteins are more specific and only make cuts at certain DNA sequences. But most elements can jump to lots and lots of different locations. Sometimes these are in junk regions between genes, other times they insert into genes themselves and cause mutations. In fact their ability to cause mutations is how they were discovered. Generally these elements are only thought to move around within a cell, in other words they move around the chromosome, but they generally do not between organisms (except of course they are inherited from parents to children). However if one organism died and its DNA was taken up by a scavenger organism, then it might be possible for the element to jump into this new organism (if they were similar enough). However this happens very very rarely, but it likely has happened a few times in evolutionary history. We know this because we can occasionally find very similar elements in different species, which is unusual. But most transposable elements are very species specific and don't tend to move around.
Try the links in the MadSci Library for more information on Molecular Biology.