MadSci Network: Biochemistry |
There are two ways that muscles can make energy to use to work; one uses oxygen and the other one doesn't. When you don't use oxygen to produce energy (ATP) a waste product is lactic acid. Muscles produce lactic acids when you exercise for a long period of time and especially when you sprint (like the 100, 200, and 400 meter dashes at track meets). Since lactic acid is an acid it makes the pH of the fluids in your body become lowered (more acidic). Your body has chemicals in it that work to soak up, or buffer, that excess acid to keep your pH normal (7.4). Your kidneys are important in increasing this chemical called bicarbonate (HCO3). Also, your lungs help out but getting rid of as much carbon dioxide as possible. There is a chemical reaction that you may have learned about that happens in many places in our bodies and works to control the acidity of our body fluids. CO2 + H20 -> H+ + HCO3- Carbon dioxide + water -> proton + bicarbonate This reaction goes both ways depending on the amounts of each chemical that you have in your body. So, if you increase the H+ you will make the reaction go backwards and lots of CO2 and H2O will be produced. So, the lungs will blow out this extra CO2. If you keep CO2 low by exhaling it then a lot of the H+ will be converted into H2O and CO2 and eventually the acid (H+) will decrease and the pH will go back to normal (it will go from below 7.4 back to 7.4). Also, like I said above, the kidneys are also working to increase HCO3 to buffer the H+. So, during exercise normally, your pH stays constant, 7.4, by having your lungs and kidneys chip in to take care of the excess acid (H+) being produced by your muscles. Reference: Human Physiology: from cells to systems. Lauralee Sherwood, 1997.
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