| MadSci Network: Anatomy |
Ear wax is produced partly by sebaceous glands of the skin lining the ear canal and also by specialized glands called ceruminous glands in the same area. It seems to be a mix of shed skin cells, fatty acids, and cholesterol. Like the secretion of sebaceous glands, it probably functions as an oily coating to prevent the dehydration of the skin and eardrum within the ear (see an article by I. Okuda in Journal of Otolaryngology, vol. 20, p. 212, 1991 "Organic composition of earwax"). Actually, the secretion of fatty molecules by skin glands such as sebaceous glands is not a trivial function. It is stimulated by stress hormones such as ACTH and causes the skin and hair to become oilier. A genetically altered strain of mouse cannot respond to stress hormones by secreting these oils. When these mice are dunked in water, their dry hair cannot shed water like normal and the mice can become extremely cold (see a review article in the journal Physiological Reviews, vol. 80, p. 979, 2000 "CRH and POMC involvement in the cutaneous response to stress" by A. Slominski).
Try the links in the MadSci Library for more information on Anatomy.