MadSci Network: Molecular Biology |
So what happens to the excised introns after splicing? Experiments have shown that for the majority of spliced genes the steady-state level of intron sequences in RNA preparations is about 10 times lower than exon sequences. This suggests that the excised introns are rapidly degraded in the cell after splicing. The intron sequences do not encode protein or serve any other useful function in the cell after being spliced. Degradation by enzymes called RNAses breakdown the intron RNA into it's ribonucleotide components for reuse in the cell.
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