MadSci Network: Cell Biology |
Jessica, Don't dispair! We'll get you through this. You are right that every human cell has 46 chromosomes except the sex-cells (egg and sperm). Every cell in your body has two sets of chromosomes - one set from your mother and one from your father. You have 2 chromosome 1's, 2 chromosome 2's, 2 chromosome 3's, .... up to 23. In mitosis, where cells are replicated, the DNA replicates before mitosis. The copy and the copied DNA are held together. When it comes time to divide, the chromosomes line up, in a single line across the cell. Then, the chromosome splits apart; one strand of DNA going to one side of the cell and one to the other side. Each strand of DNA is now called a chromosome so, each new cell has 46 chromosomes. Meiosis is divided into two parts; the first part (meiosis I)is where the chromosome number goes from 46 to 23 and the second part (meiosis II) which is very much like mitosis, where the cells with 23 chrmosomes are duplicated. In meiosis I, the like chromosomes pair up so you have 23 pairs of chromosomes. (The mother's chromosome 1 pairs up with the father's chromosome 1, the 2's pair, the 3's pair, etc.). The pairs of chromosomes line up across the cell. Then, the two chromosomes in each pair (each made up of 2 strands of DNA) separate and go to different sides of the cell. You will then have two nuclei with 23 chromosomes; one chromosome 1, 1 chromosome 2, 1 chromosome 3, etc. Then, in meiosis II, the chromosomes divide just like in mitosis. It is important to remember that all cells that aren't sex cells have two sets of chromosomes. Sex cells have one set of chromosomes. When two sex cells unite, the cell that results has two sets of chromosomes. Sure hope this helps.
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