|MadSci Network: Immunology|
This is emerging as a highly contentious issue in world health. There seems to be a huge crisis, particularly in Africa with HIV transmission and AIDS. In the West, anti-retroviral therapy (ART) has been incredibly successful in that the number of people dying of AIDS has fallen dramatically. We may have to rethink AIDS as a chronic disease rather than one which is terminal. In Africa the situation is somewhat different. These drugs are incredibly expensive and also require strict adherence to the drug regimen or risk the emergence of resistant virus. With some of these drugs, even being a few hours late with them is cause for concern. It's my understanding that many drug companies have indeed provided vast quantities of drugs at cheaper/low cost to Africa. However it is alleged that certain governments in Africa are slow to distribute them and may have even sold them back to the West at a profit. As with many healthcare issues, education is key to helping the transmission of HIV in Africa. Education and access to contraception will slow HIV transmission. As for this particular technology I have not come across it before and am not a chemist and I have no knowledge of this kind of work. I have not come across any trials or data on this either. There seems to be no published data at all. Itís generally accepted that if you have something new to report it needs to be backed up with data published and reviewed by other scientists. Until then, until you have seen the data itís very difficult to say whether new technologies work or not. I would guess that a limitation of this kind of technology is that HIV in common with all viruses is an intracellular pathogen - it is what's called an obligate parasite. It cannot live outside the cells. It divides in the cells and will cause the death of the infected T cell (the T cells orchestrate the entire immune response so the loss of huge numbers of T cells would be catastrophic). Iím not sure that these silver tetroxide compounds would be able to differentiate between an infected and uninfected cell. For looking for published data and information look at http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
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