|MadSci Network: Medicine|
Dear Steve, I admire your tenacity, your recovery, and your turning this brush with disaster into an opportunity to marvel at the complexities and wonder of the body and brain. Let me start out by saying that the Mad Scientist is NOT the place to go for medical opinions or prognosis of any type, since that obviously requires input from a physician or surgeon who knows you and your case. Let me also state that I am a PhD researcher in bone cell biology with no medical credentials, and as such, can not give anything but a general scenario on how trepanned holes behave over time. A hole such as the you describe, about 1.5 cm, is considered too large for bone to grow into and fill in an adult. That pretty much only happens in children. Instead, it fills in with scar-type cells and tissue that will not become mineralized, with some bone forming only around the rim of the hole. The extent of the bony rim varies with age and the individual. It is possible, for cosmetic and/or safety reasons, to put a plastic “plug” made of acrylic into the hole. If you think that would be a viable course in your case, then you could discuss the possibility with your physician. I hope this helps. Paul R. Odgren, Ph.D. Dept. of Cell Biology University of Massachusetts Medical School, Worcester
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