Subject: Can the murine FC receptor on Natural Killer cells bind human FC
Date: Fri Jun 24 17:10:49 2005
Posted by steve
Grade level: undergrad
School: u of Penn
City: philadelphia State/Province: pa
Country: usa
Area of science: Immunology
ID: 1119651049.Im
Message:
Wondering if you could access the ADCC potential of a human antibody in a
mouse. To do this the FC receptor on the murine NK cells will need to bind
the human antibody via it's FC chain. (murine antibody will typically bind
to murine NK cells and induce ADCC). Thanks for the help!
Re: Can the murine FC receptor on Natural Killer cells bind human FC
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