MadSci Network: Immunology

Re: Can the murine FC receptor on Natural Killer cells bind human FC

Date: Fri Jul 8 19:01:46 2005
Posted By: Peter Burrows, Faculty, Microbiology
Area of science: Immunology
ID: 1119651049.Im

I have discussed your question with our resident expert on Fc receptors 
and his conclusion:
"Murine FcR bind human IgG's.  There are some subclass preferences but 
not to the extent of presence / absence of binding."
I tried to find a literature citation where this was experimentally 
validated but was unsuccessful.

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