|MadSci Network: Anatomy|
Greetings, Below you will find everything you need to know about the Lunula. http://www.medmedia.com/o13/42.ht m http://www.nh.u ltranet.com/~thabif/html/anatomy.html Matrix. The matrix is a highly specialized epithelial structure that manufactures the bulk of the nail plate. It grows and matures like other epithelial structures and produces a highly dense and compacted stratum corneum called the nail plate. The flat, oval shaped, matrix extends from under the proximal nail fold to just beyond the proximal portion of the visible part of the nail plate. A little more than one-third of the matrix is seen through the nail plate as the white half-moon shaped lunula. The epithelium of the proximal nail fold and the proximal portion of the matrix under the nail fold makes the top portion of the nail plate. The distal matrix (lunula) makes the bottom of the nail plate that is bonded to the nail bed, it is a lighter color as it mixes with the matrix cells. The lunula. Cohen PR Department of Dermatology, University of Texas-Houston Medical School 77030, USA. http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Pu bMed&lis t_uids=8647987&dopt=Abstract The lunula is the visible portion of the distal nail matrix that extends beyond the proximal nailfold. It is white, half-moon-shaped, appears by week 14 of gestation, has unique histologic features. The lunula has a primary structural role in defining the free edge of the distal nail plate. Lunular anomalies include changes in form and structure and in color. Lunular dysmorphologic features can be characterized by macrolunula, microlunula or anolunula, and nonconvex lunula. Lunular dyschromias can be confluent or spotted or can be characterized by longitudinal colored bands that traverse the lunula. Alterations in the morphologic features or color (or both) of the lunula can be an indication of either a cutaneous or a systemic disorder. Anatomy: - nail plate: - comprised of concentrated, adherent interdigitating cells which have no nuclei or organelles; - germinal matrix: - comprised of cells which contribute to 90% growth of the new nail; - distal edge of the germinal matrix is demarcated by the edge of lunula; - there is minimal adherence of germinal matrix to the nail; - sterile matrix: - extends distal to the lunula; - responsible for adherence of nail to nail bed; http://www.medmedia.com/o13/42.ht m http://www.nh.u ltranet.com/~thabif/html/anatomy.html http://www.medmedia.com/o13/42.ht m http://www.nh.u ltranet.com/~thabif/html/anatomy.html Hope this helps . June Wingert Research Associate Lexicon Genetics The Woodlands Texas
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