MadSci Network: Biochemistry
Query:

Re: How and why does salt concentration affect the activity of enzymes?

Date: Mon Feb 8 13:34:08 1999
Posted By: Chris Larson, Post-doc/Fellow Laboratory of Genetics
Area of science: Biochemistry
ID: 918135718.Bc
Message:

Salt concentration could affect the activities of enzymes in a couple of 
ways.  First, salt concentration can have an effect on the equilibrium 
constant for the reaction being catalyzed, which does not involve the 
enzyme per se but will affect the outcome of the enzyme's activity.  
Second, depending on how the enyzme performs its catalysis of the reaction 
(general acid-base, hydrogen bonding, etc), the increased salt may enhance 
or decrease the effect of the enzyme's chemistry.  Third, some proteins are 
more or less stable as the salt concentration increases.  So, in the end, I 
can't say specifically what would happen in your case, but these are  the 
general types of issues that would affect your case.

Chris Larson





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