MadSci Network: Molecular Biology
Query:

Subject: What in detail is the dispersive model of DNA replication?

Date: Mon Sep 18 13:58:45 2000
Posted by No name entered.
Grade level: teacher/prof School: Oxford University
City: Oxford State/Province: No state entered. Country: UK
Area of science: Molecular Biology
ID: 969299925.Mb
Message:

This query is for undergraduate teaching.

What would the two strands of a duplex produced by dispersive 
replication look like?  i) Would both strands have new and old segments at 
corresponding points, so that at any given bp both strands were either old 
or new; or ii) would the two strands differ randomly in their assortment of 
new and old segments; or iii) would any parental base in one strand 
necessarily be paired with a new base in the other strand and vice versa?

Did anyone actually propose a detailed mechanism for this model before the 
Meselson-Stahl experiment?  Any references?

Thank you!



Re: What in detail is the dispersive model of DNA replication?

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