| MadSci Network: Cell Biology |
The length of meiosis differs for males and females. In females, oocyte stem cells, which are active only during embryogenesis, produce ~700,000 primary oocytes through the process of mitosis. |
These cells replicate their DNA and enter meiosis, where they arrest. By puberty, the number of primary oocytes has dropped to about 400,000. With each cycle, some of these primary
oocytes begin to grow, but generally only one reenters active meiosis. |
This cell completes meiosis I, releases a polar body, and then arrests again at metaphase II of meiosis II – this process of resumed active meiosis takes only hours (while the primary oocyte may have remained arrested in meiosis I for many decades!) The meiosis II arrested oocyte (or egg) will degenerate unless it is fertilized by a sperm. One egg is generated from each primary oocyte. |
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