MadSci Network: Neuroscience |
Sarah, This is a good question. Although there are many different causes and types of depression, there is indeed a connection between food and depression (or mood in general.) However, depression is more often caused by a lack of certain foods in a diet, rather than being caused by something that is present. There is also a connection, as you have noted, between neurotransmitters and depression. The cause of depression in the biochemical sense is usually associated with low levels of neurotransmitters (such as dopamine, norepinephrine, and serotonin) in the central nervous system. Prescription drugs used to treat depression are designed to restore normal levels of neurotransmitters. For example, the class of antidepressants known as selective serotonin reuptake inhibitors (or SSRIs) such as Prozac help to increase the levels of serotonin. It is known that carbohydrates in the diet increase the brain's production of serotonin. Also, the body needs the amino acid tryptophan, which is found in food proteins, to produce serotonin. So depression can sometimes be the result of a diet that is low in carbohydrates or tryptophan. Research has shown that there may also be a connection between depression and lack of other dietary components such as omega-3 fatty acids, vitamins B3 and B6, and magnesium. There is some speculation that stimulants can lead indirectly to depression. For example, too much caffeine in the diet can prevent someone from sleeping well. Since restful sleep is necessary for good mental health, caffeine and other stimulants can lead indirectly to depression and anxiety. As a final comment, alcohol consumption can cause both depression and aggression. Although alcohol is generally thought of as something that can brighten your mood, too much alcohol consumption can lead to depression or worsen it if it is already present. Alcohol also lowers people’s inhibitions, and for some this leads to more aggressive behavior. I hope this helps!
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